Β-氧代-3-呋喃丙酸乙酯合成路线 （共 5 条）
参考文献
Matsuura
Nippon Kagaku Zasshi, 1957 , vol. 78, p. 389,394
Chem.Abstr., 1959 , p. 21861
Full Text Show Details
Kubota; Matsuura
Journal of the Chemical Society, 1958 , p. 3667,3670
Full Text Show Details
Kubota; Ichikawa
Nippon Kagaku Zasshi, 1954 , vol. 75, p. 450,451, 455
Chem.Abstr., 1955 , p. 10261
反应条件
1: sulfuric acid 2: sodium View Scheme
参考文献
Kubota; Matsuura
Journal of the Chemical Society, 1958 , p. 3667,3670
反应条件
ethanol; sodium ethanolate Erwaermen des Reaktionsprodukts mit wss. Ammoniak und Ammoniumchlorid;
参考文献
Wul'fson; Koltschin
Zhurnal Obshchei Khimii, 1959 , vol. 29, p. 3760; engl. Ausg. S. 3719
反应条件
n-butyllithium; 1,1,1,3,3,3-hexamethyl-disilazane 1) THF, hexane, -78 deg C, 1.5 h, 2) THF, 30 min; Yield given. Multistep reaction;
参考文献
Hughes, Mark J.; Thomas, Eric J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 13 p. 1493 - 1506
反应条件
1: T=20°C;
2: With acetic acid; hydrazine
T=100°C;
3: With sodium hydroxide in water; ethyl acetate
pH=~ 10;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2006/91592 A1, 2006 ;
Location in patent: Page/Page column 122-123 ;
WO 2006/091592 A1
