4-(2-苯甲酰基-4-氯苯基)-5-甲基-4H-1,2,4-三唑-3-甲醛合成路线 （共 9 条）
反应条件
dimethyl amine in methanol 1.) ice bath, 17 h 20 min, 2.) RT, 7 h 50 min;
参考文献
Hester, Jackson B.; Rudzik, Allan D.; Voigtlander, Philip F. Von
Journal of Medicinal Chemistry, 1980 , vol. 23, # 6 p. 643 - 647
反应条件
ozone in methanol; dichloromethane T=0°C; 12 h;
参考文献
Hester Jr.
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 3 p. 575 - 581
反应条件
ruthenium(IV) oxide; sodium periodate in water; acetone T=0 - 4°C; 23.5 h;
参考文献
Hester Jr.
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 3 p. 575 - 581
反应条件
1: 34.7 percent / m-chloroperoxybenzoic acid / ethanol / 18 h / Ambient temperature 2: 87.9 percent / dimethylamine / methanol / 1.) ice bath, 17 h 20 min, 2.) RT, 7 h 50 min View Scheme
参考文献
Hester, Jackson B.; Rudzik, Allan D.; Voigtlander, Philip F. Von
Journal of Medicinal Chemistry, 1980 , vol. 23, # 6 p. 643 - 647
反应条件
ozone in methanol; dichloromethane 12 h; cooling in an ice bath;
参考文献
Hester Jr.
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 3 p. 575 - 581
反应条件
1: 74.5 percent / hydrazin hydrate / 1 h / Heating 2: 83.9 percent / xylene / 2.67 h / Heating 3: 20.8 percent / ozone in oxygen / methanol; CH2Cl2 / 12 h / cooling in an ice bath View Scheme
参考文献
Hester Jr.
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 3 p. 575 - 581
反应条件
1: 83.9 percent / xylene / 2.67 h / Heating 2: 20.8 percent / ozone in oxygen / methanol; CH2Cl2 / 12 h / cooling in an ice bath View Scheme
参考文献
Hester Jr.
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 3 p. 575 - 581
反应条件
sodium hydroxide; silver nitrate in methanol; water 18 h; Ambient temperature;
参考文献
Hester Jr.
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 3 p. 575 - 581
反应条件
ammonia in ethanol 5 h; Ambient temperature;
参考文献
Hester, Jackson B.; Rudzik, Allan D.; Voigtlander, Philip F. Von
Journal of Medicinal Chemistry, 1980 , vol. 23, # 6 p. 643 - 647
