2-氧代-1,2-二氢-3-喹啉甲腈合成路线 （共 17 条）
反应条件
1: 60 percent / conc. HCl / 1 h / Heating 2: NH2OH*HCl; aq. NaOH / ethanol / 2 h / pH 8 / Heating 3: 90 percent / Ac2O / 2 h / Heating View Scheme
参考文献
TIBOTEC PHARMACEUTICALS LTD.
Patent: WO2008/37784 A1, 2008 ;
Location in patent: Page/Page column 35; 36 ;
反应条件
acetic anhydride 2 h; Heating;
参考文献
Raj, T. Tilak; Ambekar, Sarvottam Y.
Journal of Chemical Research, Miniprint, 1988 , # 2 p. 537 - 551
反应条件
1: NH2OH*HCl; aq. NaOH / ethanol / 2 h / pH 8 / Heating 2: 90 percent / Ac2O / 2 h / Heating View Scheme
参考文献
Raj, T. Tilak; Ambekar, Sarvottam Y.
Journal of Chemical Research, Miniprint, 1988 , # 2 p. 537 - 551
反应条件
1.1: potassium carbonate / N,N-dimethyl-formamide / 0.08 h / 90 °C 1.2: 2 h / 90 °C 2.1: copper(l) iodide; L-proline; potassium carbonate / ethylene glycol / 10 h / 110 °C View Scheme
参考文献
Zhang, Xinying; Guo, Xiaojie; Fang, Liangliang; Song, Yunping; Fan, Xuesen
European Journal of Organic Chemistry, 2013 , # 36 p. 8087 - 8093
反应条件
hydrogenchloride in methanol 4 h; Heating;
参考文献
Neelima; Bhat; Bhaduri
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 2 p. 409 - 411
反应条件
manganese triacetate in xylene 4 h; Heating;
参考文献
Neelima; Bhat; Bhaduri
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 2 p. 409 - 411
反应条件
1: H2O / 30 - 35 °C / solid phase 2: Mn(OCOCH3)3 / xylene / 4 h / Heating View Scheme
参考文献
Neelima; Bhat; Bhaduri
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 2 p. 409 - 411
反应条件
in acetonitrile 0.416667 h; Reflux;
参考文献
Ukhin; Suponitskii; Gribanova; Belousova; Shepelenko
Russian Chemical Bulletin, 2010 , vol. 59, # 5 p. 1023 - 1030
反应条件
in acetonitrile 1 h; Reflux;
参考文献
Ukhin; Suponitskii; Gribanova; Belousova; Shepelenko
Russian Chemical Bulletin, 2010 , vol. 59, # 5 p. 1023 - 1030
反应条件
1: 75 percent / POCl3 / 1 h / Heating 2: 75 percent / N2H4*H2O / 5 h / Heating View Scheme
参考文献
El-Sayed, Ola A.; Aboul-Enein, Hassan Y.
Archiv der Pharmazie, 2001 , vol. 334, # 4 p. 117 - 120
