2-氧代-1,2-二氢-3-喹啉甲腈合成路线 （共 17 条）
反应条件
trichlorophosphate 1 h; Heating;
参考文献
El-Sayed, Ola A.; Aboul-Enein, Hassan Y.
Archiv der Pharmazie, 2001 , vol. 334, # 4 p. 117 - 120
反应条件
bromine in acetic acid 4 h; Heating;
参考文献
Alabaster; Bell; Campbell; Ellis; Henderson; Roberts; Ruddock; Samuels; Stefaniak
Journal of Medicinal Chemistry, 1988 , vol. 31, # 10 p. 2048 - 2056
反应条件
1: 75 percent / Br2 / acetic acid / 4 h / Heating 2: 52 percent / POCl3 / 1.5 h / Heating View Scheme
参考文献
Alabaster; Bell; Campbell; Ellis; Henderson; Roberts; Ruddock; Samuels; Stefaniak
Journal of Medicinal Chemistry, 1988 , vol. 31, # 10 p. 2048 - 2056
反应条件
sulfuric acid T=150 - 160°C; 2 h;
参考文献
El-Sayed, Ola A.; Al-Bassam, Badr A.; Hussein, Maher E.
Archiv der Pharmazie, 2002 , vol. 335, # 9 p. 403 - 410
反应条件
1: 95 percent / aq. H2SO4 / 2 h / 150 - 160 °C 2: 60 percent / POCl3 / 2 h / Heating View Scheme
参考文献
El-Sayed, Ola A.; Al-Bassam, Badr A.; Hussein, Maher E.
Archiv der Pharmazie, 2002 , vol. 335, # 9 p. 403 - 410
反应条件
1: 95 percent / aq. H2SO4 / 2 h / 150 - 160 °C 2: 60 percent / POCl3 / 2 h / Heating 3: SOCl2 / 1.5 h / Heating View Scheme
参考文献
El-Sayed, Ola A.; Al-Bassam, Badr A.; Hussein, Maher E.
Archiv der Pharmazie, 2002 , vol. 335, # 9 p. 403 - 410
反应条件
1: 90 percent / phosphorus decasulphide / pyridine / 3 h / Heating 2: 70 percent / K2CO3 / acetone / 5 h / Heating 3: 85 percent / aqu. KOH / dimethylformamide View Scheme
参考文献
Raj, T. Tilak; Ambekar, Sarvottam Y.
Journal of Chemical Research, Miniprint, 1988 , # 2 p. 537 - 551
