2-甲基-2-(4-甲基戊-3-烯基)-1,3-二氧戊环合成路线 （共 21 条）
反应条件
(i) Hg(OAc)2, (ii) NaBH4, (iii) TsOH, acetone; Multistep reaction;
参考文献
Biernacki,W.; Sobotka,W.
Polish Journal of Chemistry, 1979 , vol. 53, p. 1283 - 1286
反应条件
1: 85 percent / perbenzoic acid, Na2CO3 / benzene; CH2Cl2 / -5 - 0 °C 2: 60 percent / Jones' reagent / acetone / 0.5 h / 15 - 20 °C View Scheme
参考文献
Krishna, R. R.; Chawla, H. P. S.; Dev, Sukh
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 12 p. 1190 - 1196
反应条件
polymer-supported dicyanoketene acetal; water T=20°C; 20 h;
参考文献
Masaki; Yamada; Tanaka
Synlett, 2001 , # 8 p. 1311 - 1313
参考文献
Cornish Christopher A.; Warren, Stuart
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2585 - 2598
反应条件
pyridinium p-toluenesulfonate in benzene
Heating;
参考文献
Pu, Xiaotao; Ma, Dawei
Journal of Organic Chemistry, 2006 , vol. 71, # 17 p. 6562 - 6572
反应条件
1: 68 percent / HI / H2O
2: 70 percent / toluene-p-sulphonic acid / toluene / 24 h / Heating
3: 2.) 30percent sodium hydroxide / 1.) toluene, reflux, 2 d; 2.) water, reflux, 2 h
4: 70 percent / butyl-lithium / tetrahydrofuran / 1.) 0 degC, 15 min, 2.) -78 degC to R. T.
5: 84 percent / 50percent sodium hydride / dimethylformamide / 1 h / 50 °C
View Scheme
参考文献
Cornish Christopher A.; Warren, Stuart
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2585 - 2598
反应条件
1: 2.) 30percent sodium hydroxide / 1.) toluene, reflux, 2 d; 2.) water, reflux 2h
2: 70 percent / butyl-lithium / tetrahydrofuran / 1.) 0 degC, 15 min, 2.) -78 degC to R. T.
3: 84 percent / 50percent sodium hydride / dimethylformamide / 1 h / 50 °C
View Scheme
参考文献
Cornish Christopher A.; Warren, Stuart
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2585 - 2598
反应条件
1: 72 percent / toluene-p-sulphonic acid / toluene / 24 h / Heating
2: 2.) 30percent sodium hydroxide / 1.) toluene, reflux, 2 d; 2.) water, reflux 2h
3: 70 percent / butyl-lithium / tetrahydrofuran / 1.) 0 degC, 15 min, 2.) -78 degC to R. T.
4: 84 percent / 50percent sodium hydride / dimethylformamide / 1 h / 50 °C
View Scheme
参考文献
Cornish Christopher A.; Warren, Stuart
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2585 - 2598
反应条件
1: 70 percent / butyl-lithium / tetrahydrofuran / 1.) 0 degC, 15 min, 2.) -78 degC to R. T.
2: 84 percent / 50percent sodium hydride / dimethylformamide / 1 h / 50 °C
View Scheme
参考文献
Cornish Christopher A.; Warren, Stuart
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2585 - 2598
反应条件
1: 1.) sodium iodide; 2.) 30percent sodium hydroxide / 1.) toluene, reflux, 3 d; 2.) water, reflux, 2 h
2: 70 percent / butyl-lithium / tetrahydrofuran / 1.) 0 degC, 15 min, 2.) -78 degC to R. T.
3: 84 percent / 50percent sodium hydride / dimethylformamide / 1 h / 50 °C
View Scheme
参考文献
Cornish Christopher A.; Warren, Stuart
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2585 - 2598
