1-(3-硝基-2-吡啶)-2-吡咯烷羧酸合成路线 （共 3 条）
反应条件
triethylamine in dimethyl sulfoxide T=60°C; 18 h;
参考文献
Abou-Gharbia, Magid; Freed, Meier E.; McCaully, Ronald J.; Silver, Paul J.; Wendt, Robert L.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 12 p. 1743 - 1746
反应条件
iron; acetic acid
T=60 - 65°C; 3 h;
参考文献
Abou-Gharbia, Magid; Freed, Meier E.; McCaully, Ronald J.; Silver, Paul J.; Wendt, Robert L.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 12 p. 1743 - 1746
反应条件
1: 56 percent / glacial acetic acid, iron powder / 3 h / 60 - 65 °C
2: 65 percent / LiAlH4 / diethyl ether; tetrahydrofuran / 18 h / Heating
View Scheme
参考文献
Abou-Gharbia, Magid; Freed, Meier E.; McCaully, Ronald J.; Silver, Paul J.; Wendt, Robert L.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 12 p. 1743 - 1746
