5-(2-甲基苯基)-5-氧代戊酸合成路线 （共 8 条）
反应条件
sulfuric acid 7 h; Reflux;
参考文献
Yang, Xiao-Hui; Xie, Jian-Hua; Liu, Wei-Peng; Zhou, Qi-Lin
Angewandte Chemie - International Edition, 2013 , vol. 52, # 30 p. 7833 - 7836
Angew. Chem., 2013 , vol. 125, # 30 p. 7987 - 7990,4
参考文献
Rhone-Poulenc Rorer Limited
Patent: US6211234 B1, 2001 ;
反应条件
1: 1-bromo-2-methyl benzene With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 0.833333 h;
2: glutaric acid anhydride in tetrahydrofuran; hexane
T=-78 - 20°C;
参考文献
Yang, Xiao-Hui; Xie, Jian-Hua; Liu, Wei-Peng; Zhou, Qi-Lin
Angewandte Chemie - International Edition, 2013 , vol. 52, # 30 p. 7833 - 7836
Angew. Chem., 2013 , vol. 125, # 30 p. 7987 - 7990,4
参考文献
Ghosal et al.
Journal of Organic Chemistry, 1958 , vol. 23, p. 584
反应条件
1: diethyl ether
2: CrO3
View Scheme
参考文献
Ghosal et al.
Journal of Organic Chemistry, 1958 , vol. 23, p. 584
反应条件
1: diethyl ether
2: CrO3
View Scheme
参考文献
Ghosal et al.
Journal of Organic Chemistry, 1958 , vol. 23, p. 584
参考文献
Ghosal et al.
Journal of Organic Chemistry, 1958 , vol. 23, p. 584
参考文献
Ghosal et al.
Journal of Organic Chemistry, 1958 , vol. 23, p. 584
