1-(2-羟乙基)-2-咪唑啉酮合成路线 (共 13 条)
参考文献
Bilodeau, Mark T.; Hartman, George D.; Hoffman JR., Jacob M.; Sisko, John T.; Manley, Peter J.; Smith, Anthony M.; Tucker, Thomas J.; Lumma JR., William C.; Rodman, Leonard
Patent: US2002/137755 A1, 2002 ;
US 20020137755 A1
反应条件
1: With 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hydrogencarbonate; sodium bromide in water; acetone
T=0°C; 0.166667 h;
2: With trichloroisocyanuric acid in water; acetone
T=0 - 25°C; 12 h;
3: With hydrogenchloride in water
pH=~ 2;
参考文献
ANORMED INC.
Patent: WO2006/138350 A2, 2006 ;
Location in patent: Page/Page column 87-88 ;
WO 2006/138350 A2
反应条件
1: SOCl2
2: sodium methylate; toluene; N,N'-bis-<1,4-dioxo-1,4-dihydro-<2>naphthyl>-p-phenylenediamine
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参考文献
Rohm and Haas Co.
Patent: US2840566 , 1955 ;