3-(4-氟苯)-1-苯-1H-吡唑-4-羧酸合成路线 （共 4 条）
反应条件
pyridine; potassium permanganate in water
T=20 - 22°C;
参考文献
Bratenko; Chornous; Vovk
Russian Journal of Organic Chemistry, 2001 , vol. 37, # 4 p. 552 - 555
反应条件
1: sodium acetate / ethanol / 3 h / 50 - 60 °C
2: trichlorophosphate / 5 h / 50 - 60 °C
3: potassium permanganate / 3 h / 70 - 80 °C
View Scheme
参考文献
Sun, Jian; Lv, Xian-Hai; Qiu, Han-Yue; Wang, Yan-Ting; Du, Qian-Ru; Li, Dong-Dong; Yang, Yong-Hua; Zhu, Hai-Liang
European Journal of Medicinal Chemistry, 2013 , vol. 68, p. 1 - 9
反应条件
1: sodium acetate / ethanol / 3 h / 50 - 60 °C
2: trichlorophosphate / 5 h / 50 - 60 °C
3: potassium permanganate / 3 h / 70 - 80 °C
View Scheme
参考文献
Sun, Jian; Lv, Xian-Hai; Qiu, Han-Yue; Wang, Yan-Ting; Du, Qian-Ru; Li, Dong-Dong; Yang, Yong-Hua; Zhu, Hai-Liang
European Journal of Medicinal Chemistry, 2013 , vol. 68, p. 1 - 9
反应条件
1: trichlorophosphate / 5 h / 50 - 60 °C
2: potassium permanganate / 3 h / 70 - 80 °C
View Scheme
参考文献
Sun, Jian; Lv, Xian-Hai; Qiu, Han-Yue; Wang, Yan-Ting; Du, Qian-Ru; Li, Dong-Dong; Yang, Yong-Hua; Zhu, Hai-Liang
European Journal of Medicinal Chemistry, 2013 , vol. 68, p. 1 - 9
