4-氯-2,5-二甲氧基嘧啶合成路线 (共 4 条)
反应条件
sodium hydroxide; triethylamine; trichlorophosphate in ice-water; toluene
反应条件
1.1: 1-methyl-pyrrolidin-2-one / 2.5 h / 50 °C 2.1: hydroxylamine hydrochloride; triethylamine / acetonitrile / 2 h / 45 °C 2.2: 4 h / 5.8 - 76 °C View Scheme
参考文献
DOW AGROSCIENCES LLC; Bland, Douglas C.; Roth, Gary; Bott, Craig; Hamilton, Christopher T.; Neuman, Joseph
Patent: US2014/81023 A1, 2014 ;
参考文献
Emonds, Mark Victor Michael; Roth, Gary A.
Patent: US2002/13230 A1, 2002 ;
反应条件
hydrazine in methanol; water
T=50°C; 2 h;
参考文献
Dow AgroSciences LLC
Patent: US6362335 B1, 2002 ;
Location in patent: Example 1 ;