5-苄氧基吲哚-2-甲酸乙酯合成路线

参考文献

ARENA PHARMACEUTICALS, INC.; JONES, Robert M.; BUZARD, Daniel J.; GHARBAOUI, Tawfik; JOHNSON, Benjamin R.; KASEM, Michelle; SCHRADER, Thomas O.; STIRN, Scott
Patent: WO2011/109471 A1, 2011 ;
Location in patent: Page/Page column 118-119 ;
WO 2011/109471 A1

617-35-6丙酮酸乙酯+

52068-30-14-苄氧基苯肼盐酸盐

37033-95-75-苄氧基吲哚-2-甲酸乙酯

参考文献

Schrader, Thomas O.; Johnson, Benjamin R.; Lopez, Luis; Kasem, Michelle; Gharbaoui, Tawfik; Sengupta, Dipanjan; Buzard, Daniel; Basmadjian, Christine; Jones, Robert M.
Organic Letters, 2012 , vol. 14, # 24 p. 6306 - 6309

609-14-32-甲基乙酰乙酸乙酯

37033-95-75-苄氧基吲哚-2-甲酸乙酯

参考文献

Ash; Wragg
Journal of the Chemical Society, 1958 , p. 3887,3892
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Boehme
Journal of the American Chemical Society, 1953 , vol. 75, p. 2502

37033-95-75-苄氧基吲哚-2-甲酸乙酯

20948-66-75-(苄氧基)-1H-吲哚-2-羧肼

参考文献

Sinnur, K. H.; Siddappa, S.; Hiremath, Shivayogi P.; Purohit, Muralidhar G.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 716 - 720

37033-95-75-苄氧基吲哚-2-甲酸乙酯

1215-59-45-苄氧基吲哚

参考文献

Boehme
Journal of the American Chemical Society, 1953 , vol. 75, p. 2502

37033-95-75-苄氧基吲哚-2-甲酸乙酯

6640-09-15-苯甲氧基吲哚-2-羧酸

参考文献

European Journal of Medicinal Chemistry, , vol. 26, # 1 p. 33 - 41

37033-95-75-苄氧基吲哚-2-甲酸乙酯

133845-42-8

参考文献

Cruces, MA; Elorriaga, C; Fernandez-Alvarez, E
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 1 p. 33 - 41

37033-95-75-苄氧基吲哚-2-甲酸乙酯

24985-85-15-羟基吲哚-2-甲酸乙酯

参考文献

SmithKline Beecham Corporation
Patent: US6469046 B1, 2002 ;
US 6469046 B1

37033-95-75-苄氧基吲哚-2-甲酸乙酯

36820-80-1

参考文献

Monge; Parrado; Font; Fernandez-Alvarez
Journal of Medicinal Chemistry, 1987 , vol. 30, # 6 p. 1029 - 1035

37033-95-75-苄氧基吲哚-2-甲酸乙酯

84576-41-03,5-二氢-8-(苯基甲氧基)-4H-哒嗪并(4,5-B)吲哚-4-酮腙

参考文献

Monge; Parrado; Font; Fernandez-Alvarez
Journal of Medicinal Chemistry, 1987 , vol. 30, # 6 p. 1029 - 1035