2-苄基-1,2,3,4-四氢异喹啉-1-甲腈合成路线 (共 3 条)
反应条件
tert.-butylhydroperoxide; iodine in methanol
T=20°C; 24 h;
参考文献
Dhineshkumar, Jayaraman; Lamani, Manjunath; Alagiri, Kaliyamoorthy; Prabhu, Kandikere Ramaiah
Organic Letters, 2013 , vol. 15, # 5 p. 1092 - 1095
参考文献
Beaumont, David; Waigh, Roger D.; Sunbhanich, Methi; Nott, Michael W.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 4 p. 507 - 515
反应条件
benzoic acid in toluene
T=200°C; 0.333333 h; Microwave irradiationSealed tube; Overall yield = 63 percent; regioselective reaction;
参考文献
Ma, Longle; Chen, Weijie; Seidel, Daniel
Journal of the American Chemical Society, 2012 , vol. 134, # 37 p. 15305 - 15308