2-碘-1-甲基-1H-咪唑合成路线 （共 8 条）
反应条件
1: With methyllithium in tetrahydrofuran T=-30°C; 0.5 h; 2: With iodine in tetrahydrofuran T=20°C; 4 h;
参考文献
Park, Soon Bong; Alper, Howard
Organic Letters, 2003 , vol. 5, # 18 p. 3209 - 3212
反应条件
iodine; silver(I) acetate in dichloromethane T=50°C; Inert atmosphere;
参考文献
Iglesias, Manuel; Schuster, Oliver; Albrecht, Martin
Tetrahedron Letters, 2010 , vol. 51, # 41 p. 5423 - 5425
反应条件
palladium diacetate; triethylamine; acrylic acid methyl ester; triphenylphosphine in N,N-dimethyl-formamide T=140°C; 72 h;
参考文献
Kerherve, Jennifer; Botuha, Candice; Dubois, Joelle
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 10 p. 2214 - 2222
反应条件
sulfuric acid; nitric acid 1.) 0 deg C, 2.) room temperature, 3 h;
参考文献
Dickens; Dyer; Hamill; et al.
Journal of Organic Chemistry, 1981 , vol. 46, # 9 p. 1781 - 1786
反应条件
chloro-trimethyl-silane; ethylene dibromide; zinc; bis(dibenzylideneacetone)-palladium(0) 1.) THF, room temperature, 1 h, 2.) THF, 25 deg C, 48 h; Yield given. Multistep reaction;
参考文献
Prasad, A. S. Bhanu; Stevenson, Thomas M.; Citineni, Janakiram Rao; Nyzam, Valerie; Knochel, Paul
Tetrahedron, 1997 , vol. 53, # 21 p. 7237 - 7254
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in N,N-dimethyl-formamide T=130°C; Suzuki coupling; 3 h; Inert atmosphere;
参考文献
Kerherve, Jennifer; Botuha, Candice; Dubois, Joelle
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 10 p. 2214 - 2222
反应条件
tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide T=130°C; Stille coupling; 2 h; Inert atmosphere;
参考文献
Kerherve, Jennifer; Botuha, Candice; Dubois, Joelle
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 10 p. 2214 - 2222
反应条件
copper in N,N-dimethyl-formamide
Ullmann coupling; 4 h; Heating;
参考文献
Park, Soon Bong; Alper, Howard
Organic Letters, 2003 , vol. 5, # 18 p. 3209 - 3212
