三-o-乙酰基-5-脱氧-d-呋喃核糖合成路线 （共 24 条）
反应条件
1: 1N HCl / H2O / 2 h / 110 °C 2: pyridine / 20 h / 20 °C View Scheme
参考文献
Kiss; D'Souza; Van Koeveringe; Arnold
Helvetica Chimica Acta, 1982 , vol. 65, # 5 p. 1522 - 1537
反应条件
1: Ac2O/DMSO / 20 h / Ambient temperature 2: NaBH4 / ethanol; H2O / Ambient temperature 3: 0.4N HCl / 1.) 95 deg C, 90 min; 2.) RT, 30 min 4: pyridine / 20 h / 20 °C View Scheme
参考文献
Kiss; D'Souza; Van Koeveringe; Arnold
Helvetica Chimica Acta, 1982 , vol. 65, # 5 p. 1522 - 1537
反应条件
1: 0.4N HCl / 1.) 95 deg C, 90 min; 2.) RT, 30 min 2: pyridine / 20 h / 20 °C View Scheme
参考文献
Kiss; D'Souza; Van Koeveringe; Arnold
Helvetica Chimica Acta, 1982 , vol. 65, # 5 p. 1522 - 1537
反应条件
Yield given. Multistep reaction;
参考文献
Carbohydrate Research, , vol. 184, p. 250 - 253
反应条件
Yield given. Multistep reaction;
参考文献
Carbohydrate Research, , vol. 184, p. 250 - 253
反应条件
in hexane; isopropyl alcohol T=-10 - 5°C; 3 h; Purification / work up;
参考文献
HANMI PHARM. CO., LTD.
Patent: WO2008/105593 A1, 2008 ;
Location in patent: Page/Page column 11-12 ;
反应条件
pyridine; sulfuric acid in di-isopropyl ether T=0°C; 2 h; Cooling with ice; Product distribution / selectivity;
参考文献
API Corporation
Patent: EP2210896 A1, 2010 ;
Location in patent: Page/Page column 25 ;
反应条件
in hexane; isopropyl alcohol T=-10 - 5°C; 3 h; Purification / work up;
参考文献
HANMI PHARM. CO., LTD.
Patent: WO2008/105593 A1, 2008 ;
Location in patent: Page/Page column 11-12 ;
反应条件
pyridine; sulfuric acid in di-isopropyl ether T=0°C; 2 h; Cooling with ice; Product distribution / selectivity;
参考文献
API Corporation
Patent: EP2210896 A1, 2010 ;
Location in patent: Page/Page column 25 ;
反应条件
1: in acetonitrile Inert atmosphere; 2: With chloro-trimethyl-silane; 1,1,1,3,3,3-hexamethyl-disilazane in acetonitrile T=20°C; 0.5 h; 3: With trimethylsilyl trifluoromethanesulfonate in acetonitrile T=-78 - 20°C;
参考文献
Coll Farma S.L.
Patent: EP2241556 A1, 2010 ;
Location in patent: Page/Page column 9 ;
