(R)-3-氨基-3-苯基 丙酸甲酯合成路线 （共 7 条）
反应条件
1: 75 percent / NaHCO3 / CH2Cl2; H2O 2: 1.)KHMDS; 2.) MoOPH / 1.) toluene, THF, -78 deg C to -25 deg C; 2.) toluene, THF, -60 deg C, 3 h View Scheme
参考文献
Hanessian; Sanceau
Canadian Journal of Chemistry, 1996 , vol. 74, # 4 p. 621 - 624
反应条件
hydrogenchloride T=140°C; 6 h;
参考文献
Terracciano, Stefania; Bruno, Ines; D'Amico, Elisabetta; Bifulco, Giuseppe; Zampella, Angela; Sepe, Valentina; Smith, Charles D.; Riccio, Raffaele
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 13 p. 6580 - 6588
反应条件
hydrogenchloride T=140°C; 6 h;
参考文献
Terracciano, Stefania; Bruno, Ines; D'Amico, Elisabetta; Bifulco, Giuseppe; Zampella, Angela; Sepe, Valentina; Smith, Charles D.; Riccio, Raffaele
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 13 p. 6580 - 6588
反应条件
hydrogenchloride T=140°C; 6 h;
参考文献
Terracciano, Stefania; Bruno, Ines; D'Amico, Elisabetta; Bifulco, Giuseppe; Zampella, Angela; Sepe, Valentina; Smith, Charles D.; Riccio, Raffaele
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 13 p. 6580 - 6588
反应条件
1: 75 percent / NaHCO3 / CH2Cl2; H2O 2: 1.)KHMDS; 2.) MoOPH / 1.) toluene, THF, -78 deg C to -25 deg C; 2.) toluene, THF, -60 deg C, 3 h View Scheme
参考文献
Hanessian; Sanceau
Canadian Journal of Chemistry, 1996 , vol. 74, # 4 p. 621 - 624
反应条件
sodium tetrahydroborate in tetrahydrofuran
参考文献
Tse, Man Kin; Bhor, Santosh; Klawonn, Markus; Anilkumar, Gopinathan; Jiao, Haijun; Doebler, Christian; Spannenberg, Anke; Magerlein, Wolfgang; Hugl, Herbert; Beller, Matthias
Chemistry - A European Journal, 2006 , vol. 12, # 7 p. 1855 - 1874
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in tetrahydrofuran
参考文献
Davis, Franklin A.; Szewczyk, Joanna M.
Tetrahedron Letters, 1998 , vol. 39, # 33 p. 5951 - 5954
