1H-吡咯并[2,3-c]吡啶-1-羧酸叔丁酯合成路线 （共 4 条）
反应条件
bis(η4-1,5-cyclooctadiene)-di-μ-methoxy-diiridium(I); 4,4'-di-tert-butyl-2,2'-dipyridyl in tetrahydrofuran T=55°C; 20 h; Inert atmosphere; regioselective reaction;
参考文献
Kallepalli, Venkata A.; Shi, Feng; Paul, Sulagna; Onyeozili, Edith N.; Maleczka Jr., Robert E.; Smith III, Milton R.
Journal of Organic Chemistry, 2009 , vol. 74, # 23 p. 9199 - 9201
反应条件
triethylamine
T=0 - 20°C; 3 h;
参考文献
SUNSHINE LAKE PHARMA CO., LTD.; ZHANG, Jiancun; ZHANG, Yingjun; ZHANG, Weihong; LIU, Bing; ZHANG, Jiquan; LIU, Jinlei; ZHANG, Lu
Patent: WO2013/71697 A1, 2013 ;
Location in patent: Paragraph 00268 ;
反应条件
triethylamine in dichloromethane
参考文献
Schrimpf, Michael R.; Tietje, Karin R.; Toupence, Richard B.; Ji, Jianguo; Basha, Anwer; Bunnelle, William H.; Daanen, Jerome F.; Pace, Jennifer M.; Sippy, Kevin B.
Patent: US2002/19388 A1, 2002 ;
反应条件
Adam's catalyst; hydrogen; acetic acid in ethanol
P=15001.5 Torr;
参考文献
SUNSHINE LAKE PHARMA CO., LTD.; ZHANG, Jiancun; ZHANG, Yingjun; ZHANG, Weihong; LIU, Bing; ZHANG, Jiquan; LIU, Jinlei; ZHANG, Lu
Patent: WO2013/71697 A1, 2013 ;
Location in patent: Paragraph 00269 ;
