4,4,4-三氟丁酸乙酯合成路线 （共 17 条）
反应条件
hydrogen; palladium on activated charcoal in diethyl ether T=25°C; P=750.06 Torr; 6 h; ultrasound;
参考文献
Carcenac; Tordeux; Wakselman; Diter
Journal of Fluorine Chemistry, 2005 , vol. 126, # 9-10 p. 1347 - 1355
反应条件
triethylamine; bis-triphenylphosphine-palladium(II) chloride T=80°C; P=22800 Torr; 24 h; other conditions;
参考文献
Urata, Hisao; Kosukegawa, Osamu; Ishii, Yoshimitsu; Yugary, Hideki; Fuchikami, Takamasa
Tetrahedron Letters, 1989 , vol. 30, # 33 p. 4403 - 4406
反应条件
1: anhydrous trifluoroacetaldehyde With sodium hydrogencarbonate; magnesium sulfate in tert-butyl methyl ether; water T=10°C; 0.166667 h; 2: 4,4,4-trifluoro-2-(triphenyl-λ5-phosphanylidene)butyric acid ethyl ester With magnesium sulfate in tert-butyl methyl ether; water T=70 - 75°C; P=930.891 - 1086.04 Torr; 15 h;
参考文献
Alirnardanov, Asaf; Schmid, Jean; Afragola, Jay; Khafizova, Gulnaz
Organic Process Research and Development, 2008 , vol. 12, # 3 p. 424 - 428
反应条件
hydrogen; palladium on activated charcoal in acetic acid
参考文献
Filler,R.; Naqvi,S.M.
Tetrahedron, 1963 , vol. 19, p. 879 - 889
反应条件
1: 80 percent / phosphorus pentaoxide 2: 84 percent / hydrogen / platinum oxide / diethyl ether / 8 h / 3040 Torr View Scheme
参考文献
Ratier, Max; Pereyre, Michel; Davies, Alwyn G.; Sutcliffe, Roger
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1984 , p. 1907 - 1916
反应条件
1: 68 percent / sodium borohydride 2: 80 percent / phosphorus pentaoxide 3: 84 percent / hydrogen / platinum oxide / diethyl ether / 8 h / 3040 Torr View Scheme
参考文献
Ratier, Max; Pereyre, Michel; Davies, Alwyn G.; Sutcliffe, Roger
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1984 , p. 1907 - 1916
参考文献
McBee et al.
Journal of the American Chemical Society, 1950 , vol. 72, p. 5071
参考文献
McBee et al.
Journal of the American Chemical Society, 1950 , vol. 72, p. 5071
反应条件
bis-triphenylphosphine-palladium(II) chloride in acetonitrile T=100°C; P=83600.1 Torr; 62 h; var. catalysts, var. times, var. solvents, other temp.: 120 degC; other reaction partners: MeOH, i-PrOH; Product distributionMechanism;
参考文献
Fuchikami, Takamasa; Ohishi, Katsuyuki; Ojima, Iwao
Journal of Organic Chemistry, 1983 , vol. 48, # 21 p. 3803 - 3807
反应条件
sodium tetrahydroborate in ethylene glycol dimethyl ether var. solv.: DG, THF;
参考文献
Dedek, Vaclav; Liska, Frantisek; Fikar, Jiri; Barta, Milan; Kasparova, Marie; et. al
Journal of Fluorine Chemistry, 1985 , vol. 29, p. 151
