1: With hydrogenchloride; sodium sulfate in water 1 h; 2: With hydroxylamine hydrochloride in water T=10 - 80°C; 1.5 h; 3: With sulfuric acid T=60°C; 6 h;
1: 4-chloro-aniline With hydrogenchloride; sodium nitrite in water T=0°C; 0.5 h; Cooling with ice; 2: 4-fluoroaniline With hydrogenchloride; titanium(III) chloride in water 0.25 h; Inert atmosphere; 3: With sodium hydroxide; sodium sulfite in water regioselective reaction;
参考文献
Wetzel, Alexander; Ehrhardt, Varinia; Heinrich, Markus R.
Angewandte Chemie - International Edition, 2008 , vol. 47, # 47 p. 9130 - 9133
