对氟苯硫酚合成路线

1207756-58-8((2R,3S,5R)-3-乙酰氧基-5-(3-(5-氰基-6-(4-氟苯基硫代)烟酰基)脲啶)四氢呋喃-2-基)甲基乙酸酯

参考文献

Fan, Xuesen; Feng, Dong; Wang, Xia; Qu, Yingying; Zhang, Xinying
Heteroatom Chemistry, 2009 , vol. 20, # 6 p. 362 - 368

参考文献

BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG
Patent: WO2005/49559 A2, 2005 ;
Location in patent: Page/Page column 19 ;
WO 2005/049559 A2

1207756-61-35-氰基-6-(4-氟苯基硫代)-N-((2R,4S,5R)-4-羟基-5-(羟基甲基)四氢呋喃-2-基氨基甲酰)烟酰胺

参考文献

Fan, Xuesen; Feng, Dong; Wang, Xia; Qu, Yingying; Zhang, Xinying
Heteroatom Chemistry, 2009 , vol. 20, # 6 p. 362 - 368

371-42-6对氟苯硫酚

179420-17-8

参考文献

Norris, Timothy; Leeman, Kyle
Organic Process Research and Development, 2008 , vol. 12, # 5 p. 869 - 876

75-30-92-碘代丙烷+

371-42-6对氟苯硫酚

702-13-6

参考文献

PFIZER INC.; ASPNES, Gary Erik; DIDIUK, Mary Theresa; GUZMAN-PEREZ, Angel; MAGUIRE, Robert John
Patent: WO2011/158149 A1, 2011 ;
Location in patent: Page/Page column 40 ;
WO 2011/158149 A1

371-42-6对氟苯硫酚+

107-08-41-碘丙烷

702-19-2

参考文献

MERCK SERONO S.A.; CROSIGNANI, Stefano; JORAND-LEBRUN, Catherine; CLEVA, Christophe; PRETRE, Adeline
Patent: WO2010/92043 A1, 2010 ;
Location in patent: Page/Page column 106 ;

371-42-6对氟苯硫酚+

82420-34-64-溴-2-硝基苄基溴

651780-34-6

参考文献

SMITHKLINE BEECHAM CORPORATION
Patent: WO2004/10995 A1, 2004 ;
Location in patent: Page/Page column 54 ;
WO 2004/010995 A1

371-42-6对氟苯硫酚

81851-08-3

参考文献

John Wyeth and Brother Limited
Patent: US4327102 A1, 1982 ;

371-42-6对氟苯硫酚

820975-37-9

参考文献

Mesangeau, Christophe; Fraise, Mikael; Delagrange, Philippe; Caignard, Daniel Henri; Boutin, Jean Albert; Berthelot, Pascal; Yous, Said
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 5 p. 1835 - 1840

371-42-6对氟苯硫酚

820975-39-1

参考文献

Mesangeau, Christophe; Fraise, Mikael; Delagrange, Philippe; Caignard, Daniel Henri; Boutin, Jean Albert; Berthelot, Pascal; Yous, Said
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 5 p. 1835 - 1840