2-甲基-4-噻唑乙酸乙酯合成路线 （共 10 条）
参考文献
Burger; Ullyot
Journal of Organic Chemistry, 1947 , vol. 12, p. 342,351
Full Text Show Details
Jones; Robinson; Strachan
Journal of the Chemical Society, 1946 , p. 91
反应条件
lithium hydroxide; water in tetrahydrofuran T=23°C; Heating / reflux;
参考文献
VICURON PHARMACEUTICALS INC.
Patent: US2006/211603 A1, 2006 ;
Location in patent: Page/Page column 71 ;
参考文献
Takasugi, Hisashi; Terasawa, Takeshi; Inoue, Yoshikazu; Nakamura, Hideko; Nagayoshi, Akira; Ohtake, Hiroaki; Furukawa, Yoshiro; Mikami, Masafumi; Hinoue, Kazumasa; Ohtsubo, Makoto
Patent: US2004/58903 A1, 2004 ;
反应条件
1: aqueous NH3 2: POCl3 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 12, p. 342,351
反应条件
in ethanol
5 h; Heating / reflux;
参考文献
DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1479681 A1, 2004 ;
Location in patent: Page 85 ;
参考文献
Jones et al.
Journal of the American Chemical Society, 1946 , p. 87,91
Full Text Show Details
Burger; Ullyot
Journal of Organic Chemistry, 1947 , vol. 12, p. 342,351
反应条件
1: bromine
2: ethanol
View Scheme
参考文献
Burger; Ullyot
Journal of Organic Chemistry, 1947 , vol. 12, p. 342,351
参考文献
Arakawa,K. et al.
Chemical and Pharmaceutical Bulletin, 1972 , vol. 20, p. 1041 - 1046
反应条件
1: acetone; diethyl ether
2: acetic acid
View Scheme
参考文献
Arakawa,K. et al.
Chemical and Pharmaceutical Bulletin, 1972 , vol. 20, p. 1041 - 1046
参考文献
Steude
Justus Liebigs Annalen der Chemie, 1891 , vol. 261, p. 35,39
