alpha-溴苯基乙酸甲酯合成路线 （共 64 条）
反应条件
silver trifluoromethanesulfonate in dichloromethane T=-78 - 23°C; Friedel Crafts alkylation; 20 h; Inert atmosphere;
参考文献
Lai, Ping-Shan; Dubland, Joshua A.; Sarwar, Mohammed G.; Chudzinski, Michael G.; Taylor, Mark S.
Tetrahedron, 2011 , vol. 67, # 39 p. 7586 - 7592
反应条件
1: With zinc in tetrahydrofuran Heating; 2: With (3,5-dinitrophenyl)(4-methylpiperazin-1-yl)methanone; copper(I) bromide dimethylsulfide complex in N,N-dimethyl acetamide T=22°C; 1 h;
参考文献
Su, Xianbin; Fox, David J.; Blackwell, David T.; Tanaka, Kiyotaka; Spring, David R.
Chemical Communications, 2006 , # 37 p. 3883 - 3885
反应条件
1: ethanol; N,N-dimethyl-formamide / 1.2 h / 20 °C / Microwave irradiation 2: triethylamine / ethanol; water / 5.3 h / Microwave irradiation View Scheme
参考文献
Baile; Mahajan
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2012 , vol. 51, # 6 p. 891 - 894
反应条件
ammonium chloride; zinc in ethanol T=80°C; 0.00833333 h; microwave irradiation;
参考文献
Li, Jian; Ye, Deju; Liu, Hong; Luo, Xiaoming; Jiang, Hualiang
Synthetic Communications, 2008 , vol. 38, # 4 p. 567 - 575
反应条件
potassium fluoride; ((S)-2,2′-bis(diphenylphosphino)-1,1′-binaphthyl)PdCl2*2THF in 1,4-dioxane T=100°C;
参考文献
Lei, Aiwen; Zhang, Xumu
Tetrahedron Letters, 2002 , vol. 43, # 14 p. 2525 - 2528
反应条件
1: (i) NaOMe, DMSO, (ii) /BRN= 1102743/ 2: LiAlH4 / diethyl ether View Scheme
参考文献
Clauson-Kaas,N. et al.
Acta Chemica Scandinavica (1947-1973), 1969 , vol. 23, p. 2322 - 2324
反应条件
(i) NaOMe, DMSO, (ii) /BRN= 1102743/; Multistep reaction;
参考文献
Clauson-Kaas,N. et al.
Acta Chemica Scandinavica (1947-1973), 1969 , vol. 23, p. 2322 - 2324
反应条件
sodium methylate; potassium carbonate; potassium iodide 1.) acetone, reflux, 12 h; 2.) benzene, reflux, 7 h; Yield given. Multistep reaction;
参考文献
Olagbemiro, T.O.; Nyakutse, C.A.; Lajide, L.; Agho, M.O.; Chukwu, C.E.
Bulletin des Societes Chimiques Belges, 1987 , vol. 96, # 6 p. 473 - 480
反应条件
1: KF, AcNH2 / 6 h / 120 °C 2: KOH / methanol View Scheme
参考文献
Cavalleri,B. et al.
Farmaco, Edizione Scientifica, 1968 , vol. 23, p. 1127 - 1140
反应条件
4-methoxy pyridine; Ru(bpy)3Cl2; lithium carbonate in N,N-dimethyl acetamide T=25°C; 24 h; Irradiation;
参考文献
Su, Yijin; Zhang, Liangren; Jiao, Ning
Organic Letters, 2011 , vol. 13, # 9 p. 2168 - 2171
