BOC-L-3,4二羟基苯丙氨酸苄酯合成路线 （共 3 条）
反应条件
potassium hydrogencarbonate in N,N-dimethyl-formamide
T=20°C; 7 h; Inert atmosphere;
参考文献
ONO PHARMACEUTICALS CO., LTD.; Kokubo, Masaya; Yano, Koji
Patent: US2013/245074 A1, 2013 ;
Location in patent: Paragraph 0356-0358 ;
反应条件
1.1: triethylamine / water; tetrahydrofuran / 14 h / 20 °C / |Inert atmosphere
1.2: |Cooling with ice
2.1: potassium hydrogencarbonate / N,N-dimethyl-formamide / 7 h / 20 °C / |Inert atmosphere
View Scheme
参考文献
ONO PHARMACEUTICALS CO., LTD.; Kokubo, Masaya; Yano, Koji
Patent: US2013/245074 A1, 2013 ;
反应条件
1.1: triethylamine / water; tetrahydrofuran / 14 h / 20 °C / |Inert atmosphere
1.2: |Cooling with ice
2.1: potassium hydrogencarbonate / N,N-dimethyl-formamide / 7 h / 20 °C / |Inert atmosphere
View Scheme
参考文献
ONO PHARMACEUTICALS CO., LTD.; Kokubo, Masaya; Yano, Koji
Patent: US2013/245074 A1, 2013 ;
