1-(苯基磺酰基)-5-甲氧基-4-氮杂吲哚合成路线 （共 3 条）
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in dichloromethane
T=0 - 20°C; 2.25 h;
参考文献
Larraya, Carlos; Guillard, Jerome; Renard, Pierre; Audinot, Valerie; Boutin, Jean A.; Delagrange, Philippe; Bennejean, Caroline; Viaud-Massuard, Marie-Claude
European Journal of Medicinal Chemistry, 2004 , vol. 39, # 6 p. 515 - 526
反应条件
1: 94 percent / potassium tert-butoxide / tetrahydrofuran / 3.5 h / -10 °C
2: 71 percent / hydrogen / palladium on charcoal / ethanol / 5 h / 20 °C / 2327.17 Torr
3: 99 percent / sodium hydroxide / benzyltriethylammonium chloride / CH2Cl2 / 2.25 h / 0 - 20 °C
View Scheme
参考文献
Larraya, Carlos; Guillard, Jerome; Renard, Pierre; Audinot, Valerie; Boutin, Jean A.; Delagrange, Philippe; Bennejean, Caroline; Viaud-Massuard, Marie-Claude
European Journal of Medicinal Chemistry, 2004 , vol. 39, # 6 p. 515 - 526
反应条件
1: 71 percent / hydrogen / palladium on charcoal / ethanol / 5 h / 20 °C / 2327.17 Torr
2: 99 percent / sodium hydroxide / benzyltriethylammonium chloride / CH2Cl2 / 2.25 h / 0 - 20 °C
View Scheme
参考文献
Larraya, Carlos; Guillard, Jerome; Renard, Pierre; Audinot, Valerie; Boutin, Jean A.; Delagrange, Philippe; Bennejean, Caroline; Viaud-Massuard, Marie-Claude
European Journal of Medicinal Chemistry, 2004 , vol. 39, # 6 p. 515 - 526
