4-(4-羟基-6-氧代-1,6-二氢嘧啶-2-基氨基)苯甲腈合成路线

374067-80-84-(4-羟基-6-氧代-1,6-二氢嘧啶-2-基氨基)苯甲腈

参考文献

Ludovici, Donald W.; De Corte, Bart L.; Kukla, Michael J.; Ye, Hong; Ho, Chih Y.; Lichtenstein, Mark A.; Kavash, Robert W.; Andries, Koen; De Bethune, Marie-Pierre; Azijn, Hilde; Pauwels, Rudi; Lewi, Paul J.; Heeres, Jan; Koymans, Lucien M.H.; De Jonge, Marc R.; Van Aken, Koen J.A.; Daeyaert, Frederik F.D.; Das, Kalyan; Arnold, Edward; Janssen, Paul A.J.
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 17 p. 2235 - 2239

5637-42-3N-(4-氰基苯基)胍+

105-53-3丙二酸二乙酯

374067-80-84-(4-羟基-6-氧代-1,6-二氢嘧啶-2-基氨基)苯甲腈

参考文献

HETERO RESEARCH FOUNDATION; Parthasaradhi Reddy, Bandi; Rathnakar Reddy, Kura; Muralidhara Reddy, Dasari; Raji Reddy, Rapolu; Vamsi Krishna, Bandi; Venkat Narsimha Reddy, Adulla
Patent: US2013/96148 A1, 2013 ;
Location in patent: Paragraph 0087 ;

873-74-5对氨基苯腈

374067-80-84-(4-羟基-6-氧代-1,6-二氢嘧啶-2-基氨基)苯甲腈

参考文献

HETERO RESEARCH FOUNDATION; Parthasaradhi Reddy, Bandi; Rathnakar Reddy, Kura; Muralidhara Reddy, Dasari; Raji Reddy, Rapolu; Vamsi Krishna, Bandi; Venkat Narsimha Reddy, Adulla
Patent: US2013/96148 A1, 2013 ;

374067-80-84-(4-羟基-6-氧代-1,6-二氢嘧啶-2-基氨基)苯甲腈

329187-59-94-N[2(4,6-二氯吡啶基)]-氨基苯腈

参考文献

TIBOTEC PHARMACEUTICALS LTD.
Patent: WO2008/80964 A1, 2008 ;
Location in patent: Page/Page column 27 ;

374067-80-84-(4-羟基-6-氧代-1,6-二氢嘧啶-2-基氨基)苯甲腈

269055-76-74-[[5-溴-6-氯-2-[(4-氰基苯基)氨基]-4-嘧啶基]氧基]-3,5-二甲基苯腈

参考文献

Ludovici, Donald W.; De Corte, Bart L.; Kukla, Michael J.; Ye, Hong; Ho, Chih Y.; Lichtenstein, Mark A.; Kavash, Robert W.; Andries, Koen; De Bethune, Marie-Pierre; Azijn, Hilde; Pauwels, Rudi; Lewi, Paul J.; Heeres, Jan; Koymans, Lucien M.H.; De Jonge, Marc R.; Van Aken, Koen J.A.; Daeyaert, Frederik F.D.; Das, Kalyan; Arnold, Edward; Janssen, Paul A.J.
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 17 p. 2235 - 2239

374067-80-84-(4-羟基-6-氧代-1,6-二氢嘧啶-2-基氨基)苯甲腈

269055-15-4依曲韦林

参考文献

HETERO RESEARCH FOUNDATION; Parthasaradhi Reddy, Bandi; Rathnakar Reddy, Kura; Muralidhara Reddy, Dasari; Raji Reddy, Rapolu; Vamsi Krishna, Bandi; Venkat Narsimha Reddy, Adulla
Patent: US2013/96148 A1, 2013 ;

374067-80-84-(4-羟基-6-氧代-1,6-二氢嘧啶-2-基氨基)苯甲腈

269055-75-64-[(5-溴-4,6-二氯-2-嘧啶)氨基]苯甲腈

参考文献

Ludovici, Donald W.; De Corte, Bart L.; Kukla, Michael J.; Ye, Hong; Ho, Chih Y.; Lichtenstein, Mark A.; Kavash, Robert W.; Andries, Koen; De Bethune, Marie-Pierre; Azijn, Hilde; Pauwels, Rudi; Lewi, Paul J.; Heeres, Jan; Koymans, Lucien M.H.; De Jonge, Marc R.; Van Aken, Koen J.A.; Daeyaert, Frederik F.D.; Das, Kalyan; Arnold, Edward; Janssen, Paul A.J.
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 17 p. 2235 - 2239