2-溴-5-氟-6-甲基吡啶合成路线 （共 3 条）
反应条件
in N,N-dimethyl-formamide
T=120°C; 16 h;
参考文献
Sui, Zhihua; Guan, Jihua; Macielag, Mark J.; Jiang, Weiqin; Zhang, Suying; Qiu, Yuhong; Kraft, Patricia; Bhattacharjee, Sheela; John, T. Matthew; Haynes-Johnson, Donna; Clancy, Joanna
Journal of Medicinal Chemistry, 2002 , vol. 45, # 19 p. 4094 - 4096
反应条件
1: 40 percent / TFA / CH2Cl2 / 20 h
2: 51 percent / dimethylformamide / 16 h / 120 °C
View Scheme
参考文献
Sui, Zhihua; Guan, Jihua; Macielag, Mark J.; Jiang, Weiqin; Zhang, Suying; Qiu, Yuhong; Kraft, Patricia; Bhattacharjee, Sheela; John, T. Matthew; Haynes-Johnson, Donna; Clancy, Joanna
Journal of Medicinal Chemistry, 2002 , vol. 45, # 19 p. 4094 - 4096
反应条件
1: 40 percent / TFA / CH2Cl2 / 20 h
2: 51 percent / dimethylformamide / 16 h / 120 °C
View Scheme
参考文献
Sui, Zhihua; Guan, Jihua; Macielag, Mark J.; Jiang, Weiqin; Zhang, Suying; Qiu, Yuhong; Kraft, Patricia; Bhattacharjee, Sheela; John, T. Matthew; Haynes-Johnson, Donna; Clancy, Joanna
Journal of Medicinal Chemistry, 2002 , vol. 45, # 19 p. 4094 - 4096
