5,8-二甲氧基-3,4-二氢-1H-2-萘酮合成路线 （共 40 条）
反应条件
1: 68 percent / NaOH / H2O / 12 h / 20 °C 2: 91 percent / m-CPBA / CH2Cl2 / 12 h / 20 °C 3: 42 percent / MgBr2*Et2O / toluene / 6 h / Heating View Scheme
参考文献
Tririya, Gasirat; Zanger, Murray
Synthetic Communications, 2004 , vol. 34, # 17 p. 3047 - 3059
反应条件
1: 46 percent / NaOH / H2O / 18 h / 20 °C 2: 24 percent / H2SO4 / 2.5 h / -5 - 0 °C View Scheme
参考文献
Tririya, Gasirat; Zanger, Murray
Synthetic Communications, 2004 , vol. 34, # 17 p. 3047 - 3059
反应条件
1: 83 percent / LAH / tetrahydrofuran / 4 h / Ambient temperature 2: pyridinium dichromate / or PCC View Scheme
参考文献
Mehendale, A. R.; Kulkarni, Alpana; Nagarajan, Geeta
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. <B> 27, # 1-12 p. 305 - 307
反应条件
hydrogenchloride; ethanol
参考文献
Grob; Wicki
Helvetica Chimica Acta, 1948 , vol. 31, p. 1706,1712
Full Text Show Details
Grob; Jundt
Helvetica Chimica Acta, 1948 , vol. 31, p. 1691,1692, 1698
Full Text Show Details
Grob; Jundt; Wicki
Helvetica Chimica Acta, 1949 , vol. 32, p. 2427,2430
参考文献
Organon Inc.
Patent: US2632024 , 1949 ;
Full Text Show Details
Organon Inc.
Patent: DE825259 , 1949 ;
DRP/DRBP Org.Chem.
反应条件
1: sodium ethylate; ethanol 2: ethanol; aqueous HCl View Scheme
参考文献
Grob; Wicki
Helvetica Chimica Acta, 1948 , vol. 31, p. 1706,1712
反应条件
1: aqueous NaOH / anschliessend Behandeln mit Dimethylsulfat 2: concentrated H2SO4 View Scheme
参考文献
Grob; Jundt
Helvetica Chimica Acta, 1952 , vol. 35, p. 2111,2113, 2114
反应条件
dipyridinium dichromate or PCC;
参考文献
Mehendale, A. R.; Kulkarni, Alpana; Nagarajan, Geeta
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. <B> 27, # 1-12 p. 305 - 307
参考文献
Grob; Jundt
Helvetica Chimica Acta, 1952 , vol. 35, p. 2111,2113, 2114
反应条件
1: 98.7 percent / ammonium carbonate / ethanol; H2O / 1 h / Heating 2: 92 percent / barium hydroxide octahydrate / H2O / 36 h / Heating View Scheme
参考文献
Ishizumi, Kikuo; Ohashi, Naohito; Tanno, Norihiko
Journal of Organic Chemistry, 1987 , vol. 52, # 20 p. 4477 - 4485
