反应条件
1.1: sodium hydroxide / water; methanol / 3.25 h / 10 - 50 °C / |Inert atmosphere
2.1: sodium hydroxide / water; isopropyl alcohol / 2.5 h / 50 - 60 °C / |Inert atmosphere
2.2: 4 h / 84 °C / |Inert atmosphere
3.1: sodium azide; triethylamine; acetic acid / 7 h / 60 - 130 °C / |Inert atmosphere
3.2: 0.25 h / 80 °C / |Inert atmosphere
View Scheme
参考文献
Bridge, Andrew W.; Jones, Ronald H.; Kabir, Humayun; Kee, Alex A.; Lythgoe, David J.; Nakach, Mustafa; Pemberton, Clive; Wrightman, John A.
Organic Process Research and Development, 2001 , vol. 5, # 1 p. 9 - 15