3-溴-4-羟基苯甲酸乙酯合成路线 （共 6 条）
反应条件
1.5 h; Heating / reflux;
参考文献
KEMIA, INC.
Patent: WO2007/75896 A2, 2007 ;
Location in patent: Page/Page column 124 ;
反应条件
N-bromosuccinmide; tetrafluoroboric acid
参考文献
Greenfield; Butera; Caufield
Tetrahedron Letters, 2003 , vol. 44, # 13 p. 2729 - 2732
反应条件
thionyl chloride man behandelt das erhaltene Chlorid mit Alkohol;
参考文献
Meyer,H.
Monatshefte fuer Chemie, 1901 , vol. 22, p. 437
反应条件
iodine; potassium carbonate in tetrahydrofuran
参考文献
Greenfield; Butera; Caufield
Tetrahedron Letters, 2003 , vol. 44, # 13 p. 2729 - 2732
反应条件
1: 2 h / 135 °C
2: 54 percent / thionyl chloride / various solvent(s) / 1.5 h / 25 °C
3: 42 percent / NaI, K2CO3 / acetonitrile / 24 h / Heating
View Scheme
参考文献
Diana, Guy D.; Oglesby, Richard C.; Akullian, Vahan; Carabateas, Phillip M.; Cutcliffe, David; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 383 - 388
反应条件
cyclohexanone; potassium carbonate
参考文献
Branch; Jones
Journal of the Chemical Society, 1955 , p. 2921,2922
