5,6,7,8-四氢-1H-苯并[4,5]噻吩并[2,3-d]嘧啶-2,4-二硫酮合成路线 （共 3 条）
反应条件
sodium hydroxide in ethanol; water
6 h; Heating;
参考文献
Sukumaran, P.; Rajasekharan, K. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1989 , vol. 28, # 1-11 p. 642 - 646
反应条件
1: With pyridine
Reflux;
2: Dimroth rearrangement; Reflux;
参考文献
Hafez, Hend N.; Hussein, Hoda A.R.; El-Gazzar, Abdel-Rahman B.A.
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 9 p. 4026 - 4034
反应条件
1: 92 percent / pyridine / 24 h / Ambient temperature
2: 96 percent / sodium hydroxide / ethanol; H2O / 6 h / Heating
View Scheme
参考文献
Sukumaran, P.; Rajasekharan, K. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1989 , vol. 28, # 1-11 p. 642 - 646
