反应条件
1.1: 98 percent / trifluoroacetic acid / CH2Cl2; H2O / 20 °C
2.1: 49 percent / diethyl azodicarboxylate; PPh3 / CH2Cl2 / 20 °C
3.1: H2 / Pd/C / tetrahydrofuran; methanol
4.1: aniline; NaNO2; NaOAc / aq. HCl; methanol; tetrahydrofuran
4.2: Na2S2O4; NaOAc / ethanol; H2O; tetrahydrofuran
5.1: 85 percent / HATU; 4-methylmorpholine / dimethylformamide
View Scheme
参考文献
Olson, Steven H.; Slossberg, Llnon H.
Tetrahedron Letters, 2003 , vol. 44, # 1 p. 61 - 63
