1-(3,5-双(三氟甲基)苯基)乙胺合成路线 （共 3 条）
反应条件
sodium hydroxide in water
参考文献
Pineiro, Jose Luis Castro; Dinnell, Kevin; Elliott, Jason Matthew; Hollingworth, Gregory John; Shaw, Duncan Edward; Swain, Christopher John; Yang, Lihu
Patent: US2003/225059 A1, 2003 ;
Location in patent: Page 21 ;
反应条件
1: With N-methoxyamine hydrochloride; sodium acetate in ethanol; water
18 h; Heating / reflux;
2: With borane-THF in tetrahydrofuran
T=0°C; 18 h; Heating / reflux;
3: With hydrogenchloride in diethyl ether
参考文献
Pineiro, Jose Luis Castro; Dinnell, Kevin; Elliott, Jason Matthew; Hollingworth, Gregory John; Shaw, Duncan Edward; Swain, Christopher John; Yang, Lihu
Patent: US2003/225059 A1, 2003 ;
Location in patent: Page 21 ;
反应条件
hydrogenchloride in 1,4-dioxane
2 h;
参考文献
MERCK and CO., INC.
Patent: WO2004/41279 A1, 2004 ;
Location in patent: Page/Page column 155 ;
WO 2004/041279 A1
