2-羟甲基-3,4-二氢吡喃合成路线 （共 17 条）
反应条件
in pyridine T=25°C; 1 h;
参考文献
Pierdet; Nedelec; Delaroff; Allais
Tetrahedron, 1980 , vol. 36, # 12 p. 1763 - 1772
参考文献
Shell Devel. Co.
Patent: US2511891 , 1948 ;
反应条件
oxalyl dichloride; dimethyl sulfoxide; triethylamine -70 deg C; Multistep reaction;
参考文献
Mohideen, Mazlin; Zulkepli, Suraya; Nik-Salleh, Nik-Salmah; Zulkefeli, Mohd; Weber, Jean-Frederic Faizal Abdullah; Rahman, A. F. M. Motiur
Archives of Pharmacal Research, 2013 , vol. 36, # 7 p. 812 - 831
反应条件
hydrogenchloride Behandeln des Reaktionsgemisches mit Natriumboranat unter Zusatz von Kaliumcarbonat;
参考文献
Shell Devel.Co.
Patent: US2768213 , 1953 ;
反应条件
1: 52 percent / diethyl ether / 64 h / -20 - -15 °C
2: 1.) 35percent H2O2, conc. H2SO4, 2.) triethylamine, acetic anhydride / 1.) THF, 20 deg C, 24 h, 2.) 20 deg C, 2 h
View Scheme
参考文献
Fehr, Charles; Galindo, Jose; Ohloff, Guenther
Helvetica Chimica Acta, 1981 , vol. 64, # 5 p. 1247 - 1256
反应条件
1: TsOH / 12 h / Ambient temperature
2: pyridine chlorochromate, CH3COONa / CH2Cl2
3: H(+), CH3CO2H, H2O
View Scheme
参考文献
Leggeri; Azzolina; Pirillo; Traverso
Farmaco, 1989 , vol. 44, # 3 p. 303 - 313
反应条件
1: Et3N / CH2Cl2 / 2 h / 0 °C
2: 28percent aq. NH3 / various solvent(s) / 15 h / 110 °C
View Scheme
参考文献
Jahangiri, Guiti K.; Reymond, Jean-Louis
Journal of the American Chemical Society, 1994 , vol. 116, # 25 p. 11264 - 11274
