2,4-二羟基-6-甲基吡啶合成路线 （共 34 条）
反应条件
sodium; methyl 4-toluenesulfonate
Reflux, 20 h; Yield given. Multistep reaction;
参考文献
Beak, Peter; Covington, Johnny B.; Smith, Stanley G.; White, J. Matthew; Zeigler, John M.
Journal of Organic Chemistry, 1980 , vol. 45, # 8 p. 1354 - 1362
反应条件
1: 4-hydroxy-6-methyl-pyridin-2(1H)-one With piperidine; pyridine in methanol; ethanol
T=25°C; 0.0833333 h;
2: benzaldehyde in methanol; ethanol
40 h; Reflux;
参考文献
Demuner, Antonio Jacinto; Valente, Vania Maria Moreira; Barbosa, Luiz Claudio Almeida; Rathi, Akshat H.; Donohoe, Timothy J.; Thompson, Amber L.
Molecules, 2009 , vol. 14, # 12 p. 4973 - 4986
反应条件
1: 56 percent / pyridine / Heating
2: dimethylformamide / Heating
View Scheme
参考文献
Mekheimer, Ramadan Ahmed; Mohamed, Nabil Helmi; Sadek, Kamal Usef
Bulletin of the Chemical Society of Japan, 1997 , vol. 70, # 7 p. 1625 - 1630
反应条件
triethylamine in ethanol
Condensation; 5 h; Heating;
参考文献
Mekheimer, Ramadan Ahmed; Mohamed, Nabil Helmi; Sadek, Kamal Usef
Bulletin of the Chemical Society of Japan, 1997 , vol. 70, # 7 p. 1625 - 1630
