3-(3-甲基苯基)丙酸合成路线 （共 19 条）
反应条件
Oxonereg;; water in tetrahydrofuran T=0 - 20°C; Hydrolysis; oxidation; 12 h;
参考文献
Orita, Akihiro; Yaruva, Jayamma; Otera, Junzo
Angewandte Chemie - International Edition, 1999 , vol. 38, # 15 p. 2267 - 2270
反应条件
sodium hydroxide; sodium amalgam
参考文献
Journal of the Chemical Society, , p. 357,362
反应条件
in xylene Decarboxylation; 4 h; Heating;
参考文献
Wigchert, Suzanne C. M.; Zwanenburg, Binne
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 18 p. 2617 - 2623
反应条件
1: pyridine / ethanol / 10 h / Heating 2: H2 / 10percent Pd/C / ethanol / 1 h / 760 Torr View Scheme
参考文献
Australian Journal of Chemistry, , vol. 43, p. 1547 - 1557
反应条件
1.1: NaH / 1,2-dimethoxy-ethane / 2 h / 20 °C 1.2: 1,2-dimethoxy-ethane / 18 h / Heating 2.1: aq. KOH / 4.5 h / Heating 3.1: aq. H2SO4 / 18 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 46, # 3 p. 399 - 408
反应条件
1: With piperidine; pyridine T=110 - 115°C; 4 h; Inert atmosphere; 2: With 5 Pd/C; hydrogen; sodium hydroxide in water T=20°C; 7 h;
参考文献
Beilstein Journal of Organic Chemistry, , vol. 8, p. 1366 - 1373
反应条件
hydrogenchloride in acetic acid 24 h; Heating; Yield given;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 31, # 9 p. 3113 - 3128
反应条件
1: KOtBu / tetrahydrofuran / 12.5 h / 20 °C 2: 92 percent / KOH / dioxane; H2O / 12 h / 20 °C 3: 88 percent / xylene / 4 h / Heating View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 18 p. 2617 - 2623
反应条件
1: 92 percent / KOH / dioxane; H2O / 12 h / 20 °C 2: 88 percent / xylene / 4 h / Heating View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 18 p. 2617 - 2623
参考文献
Journal of the American Chemical Society, , vol. 105, # 9 p. 2760 - 2770
