苯基甲基3-甲基丁-2-烯酸酯合成路线 （共 15 条）
反应条件
AD-mix-α; methanesulfonamide; sodium hydrogencarbonate; sodium sulfite in water; tert-butyl alcohol T=0 - 20°C; Inert atmosphere;
参考文献
Sharma, Vasudha; Kelly, Gilbert T.; Watanabe, Coran M. H.
Organic Letters, 2008 , vol. 10, # 21 p. 4815 - 4818
反应条件
AD-mix-α; methanesulfonamide; sodium hydrogencarbonate in water; tert-butyl alcohol T=0°C; 60 h;
参考文献
Bryant, Helen J.; Dardonville, Christophe Y.; Hodgkinson, Timothy J.; Hursthouse, Michael B.; Malik, K. M. Abdul; Shipman, Michael
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 7 p. 1249 - 1255
反应条件
1: 86 percent / AD-mix-β / Sharpless AD reaction 2: SOCl2 / CH2Cl2 3: NaIO4, RuCl3 / H2O 4: 1.) NaN3, 2.) H+ / 1.) Me2CO, H2O 5: H2 / Pd/C View Scheme
参考文献
Shao, Hui; Goodman, Murray
Journal of Organic Chemistry, 1996 , vol. 61, # 8 p. 2582 - 2583
反应条件
1: 80 percent / AD-mix-α, methanesulfonamide, NaHCO3 / H2O; 2-methyl-propan-2-ol / 60 h / 0 °C 2: 79 percent / Et3N / CH2Cl2 / 3 h / 0 °C 3: 88 percent / Na2CO3 / acetonitrile / 48 h / Heating 4: 77 percent / (+/-)camphor-10-sulfonic acid / toluene / 4 h / Ambient temperature View Scheme
参考文献
Bryant, Helen J.; Dardonville, Christophe Y.; Hodgkinson, Timothy J.; Hursthouse, Michael B.; Malik, K. M. Abdul; Shipman, Michael
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 7 p. 1249 - 1255
反应条件
[HfCl4(thf)2] in benzene
38 h; Heating;
参考文献
Ishihara, Kazuaki; Nakayama, Masaya; Ohara, Suguru; Yamamoto, Hisashi
Tetrahedron, 2002 , vol. 58, # 41 p. 8179 - 8188
反应条件
sodium acetate in toluene
T=110°C;
参考文献
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.; LONG, Timothy, Edward; PATEL, Sravan, Kumar
Patent: WO2010/68371 A2, 2010 ;
Location in patent: Page/Page column 5 ;
反应条件
potassium hydroxide; tetrabutylammomium bromide in chloroform
18 h; Heating;
参考文献
Bryant, Helen J.; Dardonville, Christophe Y.; Hodgkinson, Timothy J.; Hursthouse, Michael B.; Malik, K. M. Abdul; Shipman, Michael
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 7 p. 1249 - 1255
反应条件
[Mn(pic)3] in N,N-dimethyl-formamide
Ambient temperature;
参考文献
Narasaka, Koichi; Iwakura, Kazunori; Okauchi, Tatsuo
Chemistry Letters, 1991 , # 3 p. 423 - 426
反应条件
sodium nitrite in acetic acid
参考文献
Taniguchi,M. et al.
Chemical and Pharmaceutical Bulletin, 1972 , vol. 20, p. 1438 - 1444
反应条件
sulfuric acid in benzene
Heating;
参考文献
Taniguchi,M. et al.
Chemical and Pharmaceutical Bulletin, 1972 , vol. 20, p. 1438 - 1444
