吡啶并[3,2-d]嘧啶-2,4(1H,3H)-二酮合成路线 （共 14 条）
反应条件
aluminium trichloride in methoxybenzene T=20°C; 2 h;
参考文献
Tikad, Abdellatif; Routier, Sylvain; Akssira, Mohamed; Leger, Jean-Michel; Jarry, Christian; Guillaume, Gerald
Synlett, 2006 , # 12 p. 1938 - 1942
反应条件
sodium hydroxide T=160°C;
参考文献
Andaloussi, Mounir; Lim, Herman D.; Van Der Meer, Tiffany; Sijm, Maarten; Poulie, Chris B.M.; De Esch, Iwan J.P.; Leurs, Rob; Smits, Rogier A.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 9 p. 2663 - 2670
反应条件
ammonia in benzene 1 h;
参考文献
Heterocycles, , vol. 24, # 8 p. 2201 - 2213
反应条件
1: aqueous HCl 2: beim Erhitzen ueber den Schmelzpunkt View Scheme
参考文献
Chemische Berichte, , vol. 85, p. 1012,1019
参考文献
Fahmy, Amin Farouk; Youssef, Mohamed Salah Kamel; Halim, Mohamed Said Abdel; Hassan, Mamdouh Adly; Sauer, Jourgin
Heterocycles, 1986 , vol. 24, # 8 p. 2201 - 2213
参考文献
Journal of the American Chemical Society, , vol. 78, p. 973,974
反应条件
1: 72 percent / 48 h / Heating 2: Et3N / tetrahydrofuran / 1.5 h / -10 °C 3: NaN3 / tetrahydrofuran; H2O / 1.5 h / 0 °C 4: toluene / 2 h / Heating 5: pyridine / toluene / 24 h / Heating 6: 100 percent / AlCl3 / methoxybenzene / 2 h / 20 °C View Scheme
参考文献
Synlett, , # 12 p. 1938 - 1942
反应条件
1: Et3N / tetrahydrofuran / 1.5 h / -10 °C 2: NaN3 / tetrahydrofuran; H2O / 1.5 h / 0 °C 3: toluene / 2 h / Heating 4: pyridine / toluene / 24 h / Heating 5: 100 percent / AlCl3 / methoxybenzene / 2 h / 20 °C View Scheme
参考文献
Synlett, , # 12 p. 1938 - 1942
反应条件
1: pyridine / toluene / 24 h / Heating 2: 100 percent / AlCl3 / methoxybenzene / 2 h / 20 °C View Scheme
参考文献
Synlett, , # 12 p. 1938 - 1942
反应条件
1: triethylamine; POCl3 2: dioxane / beim Erwaermen des erhaltenen Bis-thiouronium-Salzes mit H2O 3: water; NH3 4: Raney nickel; ethanol; water; NH3 5: aqueous HCl View Scheme
参考文献
Robins; Hitchings
Journal of the American Chemical Society, 1956 , vol. 78, p. 973,974
