吡啶并[3,2-d]嘧啶-2,4(1H,3H)-二酮合成路线 （共 14 条）
反应条件
pyridine; trichlorophosphate T=180°C; P=150.015 - 900.09 Torr; 2 h; Neat (no solvent);
参考文献
Sun, Zhihua; Wang, Han; Wen, Kun; Li, Ya; Fan, Erkang
Journal of Organic Chemistry, 2011 , vol. 76, # 10 p. 4149 - 4153
反应条件
1: triethylamine; POCl3 2: dioxane / beim Erwaermen des erhaltenen Bis-thiouronium-Salzes mit H2O 3: Raney nickel; aqueous ethanol View Scheme
参考文献
Oakes et al.
Journal of the Chemical Society, 1956 , p. 1045,1053
反应条件
phosphorus pentachloride; trichlorophosphate T=160°C; Microwave irradiation;
参考文献
Andaloussi, Mounir; Lim, Herman D.; Van Der Meer, Tiffany; Sijm, Maarten; Poulie, Chris B.M.; De Esch, Iwan J.P.; Leurs, Rob; Smits, Rogier A.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 9 p. 2663 - 2670
反应条件
1: 58 percent / POCl3; PCl5 / 4 h / Heating
2: 86 percent / Bu3SnH / Pd(PPh3)4 / toluene / 1 h / 100 °C
View Scheme
参考文献
Tikad, Abdellatif; Routier, Sylvain; Akssira, Mohamed; Leger, Jean-Michel; Jarry, Christian; Guillaume, Gerald
Synlett, 2006 , # 12 p. 1938 - 1942
