5-吡嗪-2-基-3H-1,3,4-恶二唑-2-硫酮合成路线 （共 5 条）
反应条件
potassium phosphate in water
T=20°C; Reflux;
参考文献
Yan, Xu; Zhou, Shuo; Wang, Yuanqiang; Ge, Zemei; Cheng, Tieming; Li, Runtao
Tetrahedron, 2012 , vol. 68, # 38 p. 7978 - 7983
反应条件
1: sulfuric acid / |Reflux
2: hydrazine hydrate / ethanol / |Reflux
3: potassium hydroxide / ethanol / 24 h / |Reflux
View Scheme
参考文献
Zhang, Yan-Bin; Wang, Xiao-Liang; Liu, Wen; Yang, Yu-Shun; Tang, Jian-Feng; Zhu, Hai-Liang
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 21 p. 6356 - 6365
反应条件
1: hydrazine hydrate / ethanol / |Reflux
2: potassium hydroxide / ethanol / 24 h / |Reflux
View Scheme
参考文献
Zhang, Yan-Bin; Wang, Xiao-Liang; Liu, Wen; Yang, Yu-Shun; Tang, Jian-Feng; Zhu, Hai-Liang
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 21 p. 6356 - 6365
参考文献
Ambrogi; Bloch; Daturi; Logemann; Parenti
Journal of pharmaceutical sciences, 1972 , vol. 61, # 9 p. 1483 - 1486
反应条件
potassium carbonate in acetone
Reflux;
参考文献
Zhang, Yan-Bin; Wang, Xiao-Liang; Liu, Wen; Yang, Yu-Shun; Tang, Jian-Feng; Zhu, Hai-Liang
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 21 p. 6356 - 6365
