(1-苯基丙基)丙二酸二乙酯合成路线 (共 13 条)
反应条件
sodium ethanolate in ethanol 1.) 10 min, 2.) reflux, 12 h;
参考文献
Maguire, Anita R.; Buckley, N. Rachael; O'Leary, Patrick; Ferguson, George
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 24 p. 4077 - 4091
反应条件
in hexane; toluene T=-40°C; Addition; 21 h;
参考文献
Maas, Steffen; Stamm, Armin; Kunz, Horst
Synthesis, 1999 , # 10 p. 1792 - 1798
反应条件
5R,6R-isopropylidenedioxy-4,4,7,7-tetraphenyl-1,3,2-dioxaph; copper(II) bis(trifluoromethanesulfonate) in toluene T=-5°C; 3 h;
参考文献
Tetrahedron Asymmetry, , vol. 12, # 8 p. 1151 - 1157
反应条件
1: 80 percent / PBr3, pyridine / diethyl ether / 2.5 h / Ambient temperature 2: 81 percent / EtONa / ethanol / 1.) 10 min, 2.) reflux, 12 h View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 24 p. 4077 - 4091
参考文献
Journal of the American Chemical Society, , vol. 69, p. 589,591
反应条件
1: 1.) Mg / 1.) Et2O, 0 deg C, 2.) Et2O, 0 deg C, 20 min 2: 80 percent / PBr3, pyridine / diethyl ether / 2.5 h / Ambient temperature 3: 81 percent / EtONa / ethanol / 1.) 10 min, 2.) reflux, 12 h View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 24 p. 4077 - 4091
反应条件
1: 95 percent / piperidine, glacial acetic acid / ethanol / 8 h / Heating 2: 1.) Mg, 2.) cuprous bromide / 1.) ether View Scheme
参考文献
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, , vol. 29, # 1 p. 66 - 69
反应条件
1: diethyl ether 2: diethyl ether View Scheme
参考文献
American Chemical Journal, , vol. 44, p. 321
参考文献
American Chemical Journal, , vol. 44, p. 321
反应条件
magnesium; copper(I) bromide 1.) ether; Multistep reaction;
参考文献
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, , vol. 29, # 1 p. 66 - 69