1: NH3; sodium methylate; methanol 2: P2O5 View Scheme

1: aq. HCl 2: (i) SOCl2, (ii) AlCl3, CH2Cl2 View Scheme

Hydrolysis.anschliessend Decarboxylierung;

sodium ethanolate T=85°C; 18 h;

potassium acetate in water; dimethyl sulfoxide Heating;

1: 2-[(4-chlorophenyl)methyl]malonic acid diethyl ester With potassium hydride in acetonitrile T=20°C; 0.333333 h; Inert atmosphereGlovebox; 2: 4-acetylamino-2,2,6,6-tetramethylpiperidine-1-oxoammonium in acetonitrile T=24.84°C; Inert atmosphereGlovebox; Thermodynamic data;