1,2,3,6-四氢吡啶-4-硼酸频那醇酯合成路线

1198408-35-34-(6-氨基吡啶-3-基)哌啶-1-羧酸叔丁酯

参考文献

F. HOFFMANN-LA ROCHE AG; BROTHERTON-PLEISS, Christine; JAIME-FIGUEROA, Saul; LOPEZ-TAPIA, Francisco Javier; LOU, Yan; OWENS, Timothy D.
Patent: WO2013/24078 A1, 2013 ;

103966-66-15-溴-2-硝基苯甲醚+

375853-82-01,2,3,6-四氢吡啶-4-硼酸频那醇酯

1233145-65-7

参考文献

SANOFI
Patent: US2012/277220 A1, 2012 ;
Location in patent: Page/Page column 17 ;

6627-53-85-氯-2-硝基苯甲醚+

375853-82-01,2,3,6-四氢吡啶-4-硼酸频那醇酯

1233145-65-7

参考文献

Mesaros, Eugen F.; Thieu, Tho V.; Wells, Gregory J.; Zificsak, Craig A.; Wagner, Jason C.; Breslin, Henry J.; Tripathy, Rabindranath; Diebold, James L.; McHugh, Robert J.; Wohler, Ashley T.; Quail, Matthew R.; Wan, Weihua; Lu, Lihui; Huang, Zeqi; Albom, Mark S.; Angeles, Thelma S.; Wells-Knecht, Kevin J.; Aimone, Lisa D.; Cheng, Mangeng; Ator, Mark A.; Ott, Gregory R.; Dorsey, Bruce D.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 1 p. 115 - 125

375853-82-01,2,3,6-四氢吡啶-4-硼酸频那醇酯

1227068-67-81-乙酰基-5,6-二氢-2H-吡啶-4-硼酸频那醇酯

参考文献

AMGEN INC.; ALLEN, Jennifer; HORNE, Daniel B.; HU, Essa; KALLER, Matthew R.; MONENSCHEIN, Holger; NGUYEN, Thomas T.; REICHELT, Andreas; RZASA, Robert M.
Patent: WO2011/143495 A1, 2011 ;
WO 2011/143495 A1

375853-82-01,2,3,6-四氢吡啶-4-硼酸频那醇酯

1158767-08-84-(1H-吲唑-5-基)哌啶-1-羧酸叔丁酯

参考文献

MERCK SERONO S.A.; JORAND-LEBRUN, Catherine; CROSIGNANI, Stefano; DORBAIS, Jerome; GRIPPI-VALLOTTON, Tania; PRETRE, Adeline
Patent: WO2012/84704 A1, 2012 ;
WO 2012/084704 A1

375853-82-01,2,3,6-四氢吡啶-4-硼酸频那醇酯

1116228-85-3

参考文献

Mesaros, Eugen F.; Thieu, Tho V.; Wells, Gregory J.; Zificsak, Craig A.; Wagner, Jason C.; Breslin, Henry J.; Tripathy, Rabindranath; Diebold, James L.; McHugh, Robert J.; Wohler, Ashley T.; Quail, Matthew R.; Wan, Weihua; Lu, Lihui; Huang, Zeqi; Albom, Mark S.; Angeles, Thelma S.; Wells-Knecht, Kevin J.; Aimone, Lisa D.; Cheng, Mangeng; Ator, Mark A.; Ott, Gregory R.; Dorsey, Bruce D.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 1 p. 115 - 125

375853-82-01,2,3,6-四氢吡啶-4-硼酸频那醇酯

186347-72-84-苯基-3,6-二氢-2H-吡啶-1-羧酸叔丁酯

参考文献

Kim, Eunkyung; Park, Chan Sun; Han, Taedong; Bae, Myung-Ho; Chong, Wonee; Lee, Choong Hyun; Shin, Young Ah; Ahn, Byung-Nak; Kim, Mi Kyung; Shin, Chang Yell; Son, Moon Ho; Kim, Jin Kwan; Moon, Ho Sang; Shim, Hyun Joo; Kim, Eun Jung; Kim, Soon Hoe; Lim, Joong In; Lee, Chun Ho
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 18 p. 4993 - 4996

876343-87-25-溴-4-氯-2-碘-1H-吡咯并[2,3-b]吡啶+

375853-82-01,2,3,6-四氢吡啶-4-硼酸频那醇酯

876343-86-14-(5-溴-4-氯-1H-吡咯并[2,3-B]吡啶-2-基)-3,6-二氢-1(2H)-吡啶羧酸 1,1-二甲基乙酯

参考文献

Dong, Han-Qing; Foreman, Kenneth; Li, An-Hu; Mulvihill, Mark Joseph; Panicker, Bijoy; Steinig, Arno G.; Stolz, Kathryn M.; Weng, Qinghua; Jin, Meizhong; Volk, Brian; Wang, Jing; Wang, Ti; Beard, James D.
Patent: US2007/129364 A1, 2007 ;
Location in patent: Page/Page column 78 ;
US 20070129364 A1

375853-82-01,2,3,6-四氢吡啶-4-硼酸频那醇酯

844501-00-4[1-(叔丁氧基羰基)-1,2,3,6-四氢吡啶-4-基]硼酸

参考文献

INFINITY PHARMACEUTICALS, INC.; CASTRO, Alfredo, C.; EVANS, Catherine, A.; GRENIER, Louis; GROGAN, Michael, J.
Patent: WO2010/118159 A1, 2010 ;
Location in patent: Page/Page column 63; 65 ;

109-04-6邻溴吡啶+

375853-82-01,2,3,6-四氢吡啶-4-硼酸频那醇酯

90606-77-23,6-二氢-2H-[2,4]联吡啶-1-羧酸叔丁基酯

参考文献

ABBOTT LABORATORIES
Patent: WO2008/60621 A2, 2008 ;
Location in patent: Page/Page column 129 ;
WO 2008/060621 A2