3-溴-4-氟苄基氨基甲酸叔丁酯合成路线 (共 3 条)
反应条件
1: 3-bromo-4-fluoro-benzylamine hydrochloride With sodium hydroxide in tetrahydrofuran; water
0.166667 h;
2: di-tert-butyl dicarbonate in tetrahydrofuran; water
2 h;
参考文献
Glaxo Group Limited
Patent: US2009/197871 A1, 2009 ;
Location in patent: Page/Page column 80 ;
US 20090197871 A1
反应条件
sodium hydroxide; triethanolamine in dichloromethane
参考文献
Amgen Inc.
Patent: US2003/134836 A1, 2003 ;
反应条件
triethylamine in dichloromethane
参考文献
Astles, Peter C.; Eastwood, Paul R.; Houille, Olivier; Levell, Julian; Pauls, Heinz; Czekaj, Mark; Liang, Guyan; Gong, Yong; Pribish, James; Neuenschwander, Kent
Patent: US2003/187020 A1, 2003 ;