1-甲基吡咯-2-羧酸甲酯合成路线 （共 35 条）
反应条件
hydrogen; acetic acid; nickel in ethanol 0.5 h; Heating;
参考文献
Chemische Berichte, , vol. 120, p. 55 - 60
反应条件
triethylamine in acetonitrile RefluxInert atmosphere;
参考文献
Tetrahedron Letters, , vol. 51, # 31 p. 4150 - 4152
参考文献
Journal of Organic Chemistry, , vol. 20, p. 225,228
反应条件
1: butyl lithium; diethyl ether / anschliessend mit festem CO2 behandeln 2: diethyl ether View Scheme
参考文献
Journal of Organic Chemistry, , vol. 20, p. 225,228
反应条件
potassium; toluene anschliessend mit CH3I erwaermen;
参考文献
Journal of the Chemical Society, , p. 4458,4462
反应条件
1: methanol 2: potassium; toluene / anschliessend mit CH3I erwaermen View Scheme
参考文献
Journal of the Chemical Society, , p. 4458,4462
参考文献
Gazzetta Chimica Italiana, , vol. 85, p. 1430,1437
反应条件
lithium aluminium tetrahydride; diethyl ether
参考文献
Doyle et al.
Journal of the Chemical Society, 1958 , p. 4458,4462
反应条件
1: 35 percent / nitric acid, acetic anhydride / 1) -20 deg C, 6 h; 2) room temperature, 4 h 2: H2 / Ni-raney / ethanol / 12 h / 50 °C 3: 84 percent / CH2Cl2 / 12 h / Heating 4: 93 percent / aq. NaOH / methanol / 18 h / Heating View Scheme
参考文献
Bailly; Pommery; Houssin; Henichart
Journal of Pharmaceutical Sciences, 1989 , vol. 78, # 11 p. 910 - 917
反应条件
potassium hydroxide in methanol T=50°C;
参考文献
Teng, Xin; Keys, Heather; Yuan, Junying; Degterev, Alexei; Cuny, Gregory D.
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 11 p. 3219 - 3223
