反应条件
1: 1H-pyrazole-4-carboxylic acid ethyl ester With sodium hydride in N,N-dimethyl-formamide; mineral oil
0.25 h; Cooling with ice;
2: ethyl iodide in N,N-dimethyl-formamide; mineral oil
T=20°C; 1 h; Cooling with ice;
参考文献
DOMAIN THERAPEUTICS; MAYER, Stanislas; SCHANN, Stephan
Patent: WO2013/174822 A1, 2013 ;
Location in patent: Page/Page column 145 ;
