(4S)-4-甲基-5-氧代-1,3-噁唑啉-3-羧酸苄酯合成路线 （共 7 条）
反应条件
hydrogen; palladium on activated charcoal in methanol Yield given;
参考文献
Reddy, G. Vidyasagar; Rao, G. Venkat; Iyengar
Tetrahedron Letters, 1998 , vol. 39, # 14 p. 1985 - 1986
反应条件
chloro-trimethyl-silane; sodium cyanoborohydride in acetonitrile 0.25 h; Ambient temperature;
参考文献
Reddy, G. Vidyasagar; Iyengar
Chemistry Letters, 1999 , # 4 p. 299 - 300
反应条件
p-toluenesulfonic acid monohydrate; paraformaldehyde in toluene
参考文献
Mitsui Chemicals, Inc.
Patent: EP1340743 A1, 2003 ;
反应条件
toluene-4-sulfonic acid in benzene
1 h; Heating;
参考文献
Walter, Magnus W.; Adlington, Robert M.; Baldwin, Jack E.; Schofield, Christopher J.
Journal of Organic Chemistry, 1998 , vol. 63, # 15 p. 5179 - 5192
反应条件
1: 1.)isobutyl chloroformate, N-methylmorpholine; 2.)triethylamine / 1.) THF, -15 deg C, 5 min; 2.) THF, -15 deg C, 1h
2: t-butyl thiol / tetrahydrofuran / Ambient temperature; Irradiation
View Scheme
参考文献
Barton, Derek H. R.; Herve, Yolande; Potier, Pierre; Thierry, Josiane
Tetrahedron, 1988 , vol. 44, # 17 p. 5479 - 5486
反应条件
toluene-4-sulfonic acid in toluene
4 h; Ambient temperature;
参考文献
Dorow; Gingrich, Diane E.
Tetrahedron Letters, 1999 , vol. 40, # 3 p. 467 - 470
反应条件
1: CH2Cl2 / 8 h / Ambient temperature
2: silica gel / CHCl3 / 120 °C
View Scheme
参考文献
Dorow; Gingrich, Diane E.
Tetrahedron Letters, 1999 , vol. 40, # 3 p. 467 - 470
