((R)-哌啶-3-基)甲醇合成路线 （共 15 条）
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran; diethyl ether T=0 - 20°C; 0.333333 h; Heating / reflux; 2: With sodium sulfate in tetrahydrofuran; diethyl ether; water
参考文献
SCHERING CORPORATION
Patent: EP1140904 B1, 2005 ;
Location in patent: Page/Page column 33 ;
反应条件
hydrogen; palladium on activated charcoal in 1,4-dioxane Yield given;
参考文献
Tetrahedron Asymmetry, , vol. 7, # 2 p. 345 - 348
反应条件
1: LiBH4 / tetrahydrofuran 2: H2 / Pd/C / dioxane View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 7, # 2 p. 345 - 348
反应条件
1: 78 percent 2: LiBH4 / tetrahydrofuran 3: H2 / Pd/C / dioxane View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 7, # 2 p. 345 - 348
反应条件
1: H2O / 15 h / lipase P-30, O.1 M aq. NaCl, 0.1 M phosphate buffer (pH 7), 2.0 N NaOH 2: 1.) TFA / 1.) O deg C, 45 min. View Scheme
参考文献
Tetrahedron: Asymmetry, , vol. 3, # 8 p. 1049 - 1054
反应条件
trifluoroacetic acid 1.) O deg C, 45 min.; Yield given. Multistep reaction;
参考文献
Tetrahedron: Asymmetry, , vol. 3, # 8 p. 1049 - 1054
参考文献
Rivera, Jocelyn; Jayasuriya, Nilukshi; Rane, Dinanath; Keertikar; Ferreira, J.Albert; Chao, Jianping; Minor, Keith; Guzi, Timothy
Tetrahedron Letters, 2002 , vol. 43, # 49 p. 8917 - 8919
反应条件
1: tetrahydrofuran 2: Et3N / ethyl acetate 3: NaN3 / dimethylformamide View Scheme
参考文献
Sagara, Yufu; Mitsuya, Morihiro; Uchiyama, Minaho; Ogino, Yoshio; Kjmura, Toshifumi; Ohtake, Norikazu; Mase, Toshiaki
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 4 p. 437 - 440
反应条件
in 1,4-dioxane; dichloromethane
参考文献
BIOCHEMIE GESELLSCHAFT M.B.H.
Patent: EP1320525 B1, 2004 ;
