反应条件
1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / -78 °C 2: manganese(IV) oxide / dichloromethane / 3 h / 20 °C 3: dichloromethane / 12 h / 20 °C 4: caesium carbonate / N,N-dimethyl-formamide / 18 h / 60 °C 5: palladium on carbon; hydrogen / ethanol / 12 h / 760.05 Torr View Scheme
参考文献
Zaghdane, Helmi; Boyd, Michael; Colucci, John; Simard, Daniel; Berthelette, Carl; Leblanc, Yves; Wang, Zhaoyin; Houle, Robert; Levesque, Jean Francois; Molinaro, Carmela; Hamel, Martine; Stocco, Rino; Sawyer, Nicole; Sillaots, Susan; Gervais, Francois; Gallant, Michel
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 11 p. 3471 - 3474