2-(溴甲基)-1-氯-4-甲氧基苯合成路线 (共 7 条)
反应条件
potassium permanganate; hydroxide
参考文献
Journal of Organic Chemistry, , vol. 27, p. 4597 - 4601
反应条件
N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile in tetrachloromethane
21 h; Heating;
参考文献
Schertl, Sabine; Hartmann, Rolf W.; Batzl-Hartmann, Christine; Schlemmer, Richard; Spru, Thilo; Bernhardt, Guenther; Gust, Ronald; Schoenenberger, Helmut
Archiv der Pharmazie, 2001 , vol. 334, # 4 p. 125 - 137
反应条件
N-bromosuccinmide; potassium carbonate; dibenzoyl peroxide in tetrachloromethane; acetone
参考文献
The Boots Company PLC
Patent: US5519034 A1, 1996 ;
反应条件
phosphorus tribromide; benzene
参考文献
Wilkinson,R.G. et al.
Journal of Organic Chemistry, 1961 , vol. 26, p. 637 - 643
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Bhati
Tetrahedron, 1962 , vol. 18, p. 1519,1423
反应条件
1: 70 percent / N-chlorosuccinimide / acetonitrile / 72 h / 50 °C
2: NBS / AIBN / CCl4 / 4 h / Heating; irradiation
View Scheme
参考文献
Speicher, Andreas
Journal fuer Praktische Chemie - Practical Applications and Applied Chemistry (Germany), 2000 , vol. 342, # 2 p. 162 - 168
反应条件
1: LiAlH4
2: PBr3
View Scheme
参考文献
Wilkinson,R.G. et al.
Journal of Organic Chemistry, 1961 , vol. 26, p. 637 - 643
反应条件
1: (i) SOCl2, (ii) /BRN= 1098229/
2: LiAlH4
3: PBr3
View Scheme
参考文献
Wilkinson,R.G. et al.
Journal of Organic Chemistry, 1961 , vol. 26, p. 637 - 643