9-氧代-10H-吖啶-4-甲酰胺合成路线 （共 3 条）
反应条件
1: With 1,1'-carbonyldiimidazole in N,N-dimethyl-formamide
T=10°C;
2: With ammonia in chloroform; N,N-dimethyl-formamide
T=20°C; 1 h;
参考文献
GUILFORD PHARMACEUTICALS INC.
Patent: WO2005/53609 A2, 2005 ;
Location in patent: Page/Page column 16 ;
WO 2005/053609 A2
反应条件
hydrogenchloride in methanol
Yield given;
参考文献
Antonini, Ippolito; Martelli, Sante
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 2 p. 471 - 473
反应条件
1: NH3 / CH2Cl2 / 0.5 h / Ambient temperature
2: 2N HCl / methanol
View Scheme
参考文献
Antonini, Ippolito; Martelli, Sante
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 2 p. 471 - 473
