(S)-2-苯基-1-丙醇合成路线 (共 88 条)
反应条件
sodium tetrahydroborate; water in tetrahydrofuran 4 h; Ambient temperature;
参考文献
Prashad, Mahavir; Har, Denis; Kim, Hong-Yong; Repic, Oljan
Tetrahedron Letters, 1998 , vol. 39, # 39 p. 7067 - 7070
反应条件
sodium hydroxide; dihydrogen peroxide in methanol T=0 - 20°C; Oxidation;
参考文献
Mazet, Clement; Gerard, David
Chemical Communications, 2011 , vol. 47, # 1 p. 298 - 300
反应条件
1: styrene; trimethylaluminum With methylaluminoxane; (-)-(NMI)2ZrCl2 in dichloromethane; water T=23°C; 2: With oxygen in dichloromethane; water T=0 - 23°C; 3: vinyl acetate With Porcine Pancreas Lipase in tetrahydrofuran T=23°C; 7 h; Further stages.;
参考文献
Huang, Zhihong; Tan, Ze; Novak, Tibor; Zhu, Gangguo; Negishi, Ei-Ichi
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 4-5 p. 539 - 545
反应条件
sodium tetrahydroborate; water in tetrahydrofuran 4 h; Ambient temperature;
参考文献
Prashad, Mahavir; Har, Denis; Kim, Hong-Yong; Repic, Oljan
Tetrahedron Letters, 1998 , vol. 39, # 39 p. 7067 - 7070
反应条件
sodium tetrahydroborate; water in tetrahydrofuran 4 h; Ambient temperature;
参考文献
Prashad, Mahavir; Har, Denis; Kim, Hong-Yong; Repic, Oljan
Tetrahedron Letters, 1998 , vol. 39, # 39 p. 7067 - 7070
反应条件
dihydrogen peroxide; sodium hydroxide in diethyl ether T=0 - 23°C; Inert atmosphere; optical yield given as percent ee;
参考文献
Corberan, Rosa; Mszar, Nicholas W.; Hoveyda, Amir H.
Angewandte Chemie - International Edition, 2011 , vol. 50, # 31 p. 7079 - 7082
反应条件
phosphate buffer in methanol T=35 - 36°C; 2 h; lipase PRL-Sigma L-3126; Title compound not separated from byproducts;
参考文献
Matsumoto; Takeda; Iwata; Sakamoto; Ishida
Chemical and Pharmaceutical Bulletin, 1994 , vol. 42, # 6 p. 1191 - 1197
反应条件
sodium tetrahydroborate; water in tetrahydrofuran 4 h; Ambient temperature;
参考文献
Prashad, Mahavir; Har, Denis; Kim, Hong-Yong; Repic, Oljan
Tetrahedron Letters, 1998 , vol. 39, # 39 p. 7067 - 7070
反应条件
lithium aluminium tetrahydride in diethyl ether
参考文献
Coulbeck, Elliot; Eames, Jason
Synlett, 2008 , # 3 p. 333 - 338
反应条件
1: chiral (+)-ferrocene catalyst / CHCl3 / 22 h / 0 °C 2: LAH / diethyl ether / 20 °C View Scheme
参考文献
Schaefer, Carsten; Fu, Gregory C.
Angewandte Chemie - International Edition, 2005 , vol. 44, # 29 p. 4606 - 4608